R26-e(CAG-LSL-KRAB-dCas9-IRES-EGFP)

Description

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via CRISPR/Cas mediated homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi).