IL5

Description

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Validation Data

Figure1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

Figure 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

Figure 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.