PBMC mouse, CD34 mouse, Humanized Mouse Models


Human peripheral blood mononuclear cell-engrafted M-NSG mice are perfect models for short-term experiments requiring mature T cells, including immuno-oncology, and GVHD research.

Are you looking to further your preclinical studies and begin your in vivo efficacy, safety, and toxicity experiments? Applied StemCell now supplies research-ready humanized PBMC and CD34+ reconstruction mouse models ideal for infectious disease, gene therapy, hematopoiesis, drug target, and immunogenicity studies. Our humanized models are generated using our M-NSG  mice through the injection of healthy human donor peripheral blood mononuclear cells (PBMCs) or CD34+ hematopoietic stem cells (HSCs). After a few weeks of reconstruction following the injection of PBMCs or CD34+ HSCs, the mice develop a human-like immune system and are ready to be shipped.

ASC offers ready-to-use

Hu-PBMC and Hu-CD34+ Models

that can be shipped directly from our US, AAALAC accredited facility.

  • Affordable
  • Created in the U.S.A.
  • In vivo efficacy, safety, and toxicity testing services with PBMC or CD34 humanized mice are available – Inquire or visit our in vivo assay page